Clinical biomarker discovery by SWATH-MS based label-free quantitative proteomics: impact of criteria for identification of differentiators and data normalization method

BACKGROUND: SWATH-MS has emerged as the strategy of choice for biomarker discovery due to the proteome coverage achieved in acquisition and provision to re-interrogate the data. However, in quantitative analysis using SWATH, each sample from the comparison group is run individually in mass spectrome...

Descripción completa

Detalles Bibliográficos
Autores principales: Narasimhan, Mythreyi, Kannan, Sadhana, Chawade, Aakash, Bhattacharjee, Atanu, Govekar, Rukmini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545036/
https://www.ncbi.nlm.nih.gov/pubmed/31151397
http://dx.doi.org/10.1186/s12967-019-1937-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545036/
https://www.ncbi.nlm.nih.gov/pubmed/31151397
http://dx.doi.org/10.1186/s12967-019-1937-9

Ejemplares similares