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Synchronised spiking activity underlies phase amplitude coupling in the subthalamic nucleus of Parkinson's disease patients

Both phase-amplitude coupling (PAC) and beta-bursts in the subthalamic nucleus have been significantly linked to symptom severity in Parkinson's disease (PD) in humans and emerged independently as competing biomarkers for closed-loop deep brain stimulation (DBS). However, the underlying nature...

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Detalles Bibliográficos
Autores principales: Meidahl, Anders Christian, Moll, Christian K.E., van Wijk, Bernadette C.M., Gulberti, Alessandro, Tinkhauser, Gerd, Westphal, Manfred, Engel, Andreas K., Hamel, Wolfgang, Brown, Peter, Sharott, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545172/
https://www.ncbi.nlm.nih.gov/pubmed/30753889
http://dx.doi.org/10.1016/j.nbd.2019.02.005