The antidepressant effects of GM-CSF are mediated by the reduction of TLR4/NF-ĸB-induced IDO expression

BACKGROUND: Indoleamine 2, 3-dioxygenase 1 (IDO) is responsible for the progression of the kynurenine pathway. This pathway has been implicated in the pathophysiology of inflammation-induced depression in which conventional antidepressants are not effective. It has been reported that granulocyte-mac...

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Detalles Bibliográficos
Autores principales: Hemmati, Sara, Sadeghi, Mohammad Amin, Mohammad Jafari, Razieh, Yousefi-Manesh, Hasan, Dehpour, Ahmad Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545198/
https://www.ncbi.nlm.nih.gov/pubmed/31153376
http://dx.doi.org/10.1186/s12974-019-1509-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545198/
https://www.ncbi.nlm.nih.gov/pubmed/31153376
http://dx.doi.org/10.1186/s12974-019-1509-1

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