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Temporal profiling of Kv1.3 channel expression in brain mononuclear phagocytes following ischemic stroke
BACKGROUND: Microglia and CNS-infiltrating monocytes/macrophages (CNS-MPs) perform pro-inflammatory and protective anti-inflammatory functions following ischemic stroke. Selective inhibition of pro-inflammatory responses can be achieved by Kv1.3 channel blockade, resulting in a lower infarct size in...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545199/ https://www.ncbi.nlm.nih.gov/pubmed/31153377 http://dx.doi.org/10.1186/s12974-019-1510-8 |