Temporal profiling of Kv1.3 channel expression in brain mononuclear phagocytes following ischemic stroke

BACKGROUND: Microglia and CNS-infiltrating monocytes/macrophages (CNS-MPs) perform pro-inflammatory and protective anti-inflammatory functions following ischemic stroke. Selective inhibition of pro-inflammatory responses can be achieved by Kv1.3 channel blockade, resulting in a lower infarct size in...

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Detalles Bibliográficos
Autores principales: Gao, Tianwen, Raza, Syed Ali, Ramesha, Supriya, Nwabueze, Ngozi V., Tomkins, Amelia J., Cheng, Lihong, Xiao, Hailian, Yepes, Manuel, Rangaraju, Srikant
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545199/
https://www.ncbi.nlm.nih.gov/pubmed/31153377
http://dx.doi.org/10.1186/s12974-019-1510-8

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