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Arginase II activity regulates cytosolic Ca(2+) level in a p32-dependent manner that contributes to Ca(2+)-dependent vasoconstriction in native low-density lipoprotein-stimulated vascular smooth muscle cells

Although arginase II (ArgII) is abundant in mitochondria, Ca(2+)-accumulating organelles, the relationship between ArgII activity and Ca(2+) translocation into mitochondria and the regulation of cytosolic Ca(2+) signaling are completely unknown. We investigated the effects of ArgII activity on mitoc...

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Detalles Bibliográficos
Autores principales: Koo, Bon-hyeock, Hong, Dongeui, Hong, Hyeon Don, Lim, Hyun Kyo, Hoe, Kwang Lae, Won, Moo-Ho, Kim, Young Myeong, Berkowitz, Dan E., Ryoo, Sungwoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545325/
https://www.ncbi.nlm.nih.gov/pubmed/31155612
http://dx.doi.org/10.1038/s12276-019-0262-y