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Evolution of Subgenomic RNA Shapes Dengue Virus Adaptation and Epidemiological Fitness
Changes in dengue virus (DENV) genome affect viral fitness both clinically and epidemiologically. Even in the 3′ untranslated region (3′ UTR), mutations could affect subgenomic flaviviral RNA (sfRNA) production and its affinity for host proteins, which are necessary for successful viral replication....
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545344/ https://www.ncbi.nlm.nih.gov/pubmed/31154208 http://dx.doi.org/10.1016/j.isci.2019.05.019 |