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AMF siRNA treatment of keloid through inhibition signaling pathway of RhoA/ROCK1

A keloid (KD) is a benign dermal fibrotic tumor. Treatment of KDs is challenging and the recurrence rate is high; thus, there is an unmet need to explore new target sites and new treatment methods. As a tumor-associated cytokine, autocrine motility factor (AMF) can effectively stimulate the random a...

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Detalles Bibliográficos
Autores principales: Tian, Yi, Jin, Lan, Zhang, Wenhong, Ya, Zumeng, Cheng, Yuan, Zhao, Hongyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545443/
https://www.ncbi.nlm.nih.gov/pubmed/31193978
http://dx.doi.org/10.1016/j.gendis.2018.05.002