SSB1/SSB2 Proteins Safeguard B Cell Development by Protecting the Genomes of B Cell Precursors

Induction of programmed DNA damage and its recognition and repair are fundamental for B cell development. The ssDNA-binding protein SSB1 has been described in human cells as essential for the recognition and repair of DNA damage. To study its relevance for B cells, we recently developed Ssb1(−/−) an...

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Detalles Bibliográficos
Autores principales: Pfeifer, Matthias, Brem, Reto, Lippert, Timothy P., Boulianne, Bryant, Ho, Howin Ng, Robinson, Mark E., Stebbing, Justin, Feldhahn, Niklas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAI 2019
Materias:
Immune System Development
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545462/
https://www.ncbi.nlm.nih.gov/pubmed/31085591
http://dx.doi.org/10.4049/jimmunol.1801618

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545462/
https://www.ncbi.nlm.nih.gov/pubmed/31085591
http://dx.doi.org/10.4049/jimmunol.1801618

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