Apolipoprotein E Homozygous ε4 Allele Status: A Deteriorating Effect on Visuospatial Working Memory and Global Brain Structure

Theoretical background: The Apolipoprotein E (APOE) ε4 genotype is known to be one of the strongest single-gene predictors for Alzheimer disease, which is characterized by widespread brain structural degeneration progressing along with cognitive impairment. The ε4 allele status has been associated w...

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Detalles Bibliográficos
Autores principales: Goltermann, Janik, Redlich, Ronny, Dohm, Katharina, Zaremba, Dario, Repple, Jonathan, Kaehler, Claas, Grotegerd, Dominik, Förster, Katharina, Meinert, Susanne, Enneking, Verena, Schlaghecken, Emily, Fleischer, Lara, Hahn, Tim, Kugel, Harald, Jansen, Andreas, Krug, Axel, Brosch, Katharina, Nenadic, Igor, Schmitt, Simon, Stein, Frederike, Meller, Tina, Yüksel, Dilara, Fischer, Elena, Rietschel, Marcella, Witt, Stephanie H., Forstner, Andreas J., Nöthen, Markus M., Kircher, Tilo, Thalamuthu, Anbupalam, Baune, Bernhard T., Dannlowski, Udo, Opel, Nils
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545528/
https://www.ncbi.nlm.nih.gov/pubmed/31191441
http://dx.doi.org/10.3389/fneur.2019.00552

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545528/
https://www.ncbi.nlm.nih.gov/pubmed/31191441
http://dx.doi.org/10.3389/fneur.2019.00552

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