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LIF, a Novel Myokine, Protects Against Amyloid-Beta-Induced Neurotoxicity via Akt-Mediated Autophagy Signaling in Hippocampal Cells

BACKGROUND: Leukemia inhibitory factor, a novel myokine, is known to be associated with neural function, but the underlying molecular mechanism remains unclear. METHODS: HT-22 mouse hippocampal cells, primary hippocampal cells, and Drosophila Alzheimer’s disease model were used to determine the effe...

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Detalles Bibliográficos
Autores principales: Lee, Hye Jeong, Lee, Jung Ok, Lee, Yong Woo, Kim, Shin Ae, Seo, Il Hyeok, Han, Jeong Ah, Kang, Min Ju, Kim, Su Jin, Cho, Yun-Ho, Park, Joong-Jean, Choi, Jong-Il, Park, Sun Hwa, Kim, Hyeon Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545540/
https://www.ncbi.nlm.nih.gov/pubmed/31125414
http://dx.doi.org/10.1093/ijnp/pyz016