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LIF, a Novel Myokine, Protects Against Amyloid-Beta-Induced Neurotoxicity via Akt-Mediated Autophagy Signaling in Hippocampal Cells
BACKGROUND: Leukemia inhibitory factor, a novel myokine, is known to be associated with neural function, but the underlying molecular mechanism remains unclear. METHODS: HT-22 mouse hippocampal cells, primary hippocampal cells, and Drosophila Alzheimer’s disease model were used to determine the effe...
Autores principales: | Lee, Hye Jeong, Lee, Jung Ok, Lee, Yong Woo, Kim, Shin Ae, Seo, Il Hyeok, Han, Jeong Ah, Kang, Min Ju, Kim, Su Jin, Cho, Yun-Ho, Park, Joong-Jean, Choi, Jong-Il, Park, Sun Hwa, Kim, Hyeon Soo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545540/ https://www.ncbi.nlm.nih.gov/pubmed/31125414 http://dx.doi.org/10.1093/ijnp/pyz016 |
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