Cargando…

Pten controls B‐cell responsiveness and germinal center reaction by regulating the expression of IgD BCR

In contrast to other B‐cell antigen receptor (BCR) classes, the function of IgD BCR on mature B cells remains largely elusive as mature B cells co‐express IgM, which is sufficient for development, survival, and activation of B cells. Here, we show that IgD expression is regulated by the forkhead box...

Descripción completa

Detalles Bibliográficos
Autores principales: Setz, Corinna S, Khadour, Ahmad, Renna, Valerio, Iype, Joseena, Gentner, Eva, He, Xiaocui, Datta, Moumita, Young, Marc, Nitschke, Lars, Wienands, Jürgen, Maity, Palash C, Reth, Michael, Jumaa, Hassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545559/
https://www.ncbi.nlm.nih.gov/pubmed/31015337
http://dx.doi.org/10.15252/embj.2018100249