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High neurofilament levels are associated with clinically definite multiple sclerosis in children and adults with clinically isolated syndrome

BACKGROUND: A promising biomarker for axonal damage early in the disease course of multiple sclerosis (MS) is neurofilament light chain (NfL). It is unknown whether NfL has the same predictive value for MS diagnosis in children as in adults. OBJECTIVE: To explore the predictive value of NfL levels i...

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Detalles Bibliográficos
Autores principales: van der Vuurst de Vries, Roos M, Wong, Yu Yi M, Mescheriakova, Julia Y, van Pelt, E Daniëlle, Runia, Tessel F, Jafari, Naghmeh, Siepman, Theodora AM, Melief, Marie-José, Wierenga-Wolf, Annet F, van Luijn, Marvin M, Samijn, Johnny P, Neuteboom, Rinze F, Hintzen, Rogier Q
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545618/
https://www.ncbi.nlm.nih.gov/pubmed/29774770
http://dx.doi.org/10.1177/1352458518775303