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Genes located in Y-chromosomal regions important for male fertility show altered transcript levels in cryptorchidism and respond to curative hormone treatment

BACKGROUND: Undescended (cryptorchid) testes in patients with defective mini-puberty and low testosterone levels contain gonocytes that fail to differentiate normally, which impairs the development of Ad spermatogonia and ultimately leads to adult infertility. Treatment with the gonadotropin-releasi...

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Detalles Bibliográficos
Autores principales: Gegenschatz-Schmid, Katharina, Verkauskas, Gilvydas, Stadler, Michael B., Hadziselimovic, Faruk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545630/
https://www.ncbi.nlm.nih.gov/pubmed/31171972
http://dx.doi.org/10.1186/s12610-019-0089-3