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Genes located in Y-chromosomal regions important for male fertility show altered transcript levels in cryptorchidism and respond to curative hormone treatment
BACKGROUND: Undescended (cryptorchid) testes in patients with defective mini-puberty and low testosterone levels contain gonocytes that fail to differentiate normally, which impairs the development of Ad spermatogonia and ultimately leads to adult infertility. Treatment with the gonadotropin-releasi...
Autores principales: | Gegenschatz-Schmid, Katharina, Verkauskas, Gilvydas, Stadler, Michael B., Hadziselimovic, Faruk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545630/ https://www.ncbi.nlm.nih.gov/pubmed/31171972 http://dx.doi.org/10.1186/s12610-019-0089-3 |
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