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Neoadjuvant zoledronic acid for HER2-positive breast cancer: the Zo-NAnTax trial
BACKGROUND: Preclinical evidence suggests that zoledronic acid (ZOL) works synergistically with chemotherapy by enhancing anti-tumor activity. ZOL blocks the mevalonate pathway and may indirectly interact with human epidermal growth factor receptor 2 (HER2) pathway activation. The clinical efficacy...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545654/ https://www.ncbi.nlm.nih.gov/pubmed/31210800 http://dx.doi.org/10.1177/1758835919853971 |