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Effect of 3% saline and furosemide on biomarkers of kidney injury and renal tubular function and GFR in healthy subjects – a randomized controlled trial

BACKGROUND: Chloride is speculated to have nephrotoxic properties. In healthy subjects we tested the hypothesis that acute chloride loading with 3% saline would induce kidney injury, which could be prevented with the loop-diuretic furosemide. METHODS: The study was designed as a randomized, placebo-...

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Detalles Bibliográficos
Autores principales: Mose, F. H., Jörgensen, A. N., Vrist, M. H., Ekelöf, N. P., Pedersen, E. B., Bech, J. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545674/
https://www.ncbi.nlm.nih.gov/pubmed/31159750
http://dx.doi.org/10.1186/s12882-019-1342-x