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Effect of 3% saline and furosemide on biomarkers of kidney injury and renal tubular function and GFR in healthy subjects – a randomized controlled trial
BACKGROUND: Chloride is speculated to have nephrotoxic properties. In healthy subjects we tested the hypothesis that acute chloride loading with 3% saline would induce kidney injury, which could be prevented with the loop-diuretic furosemide. METHODS: The study was designed as a randomized, placebo-...
Autores principales: | Mose, F. H., Jörgensen, A. N., Vrist, M. H., Ekelöf, N. P., Pedersen, E. B., Bech, J. N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545674/ https://www.ncbi.nlm.nih.gov/pubmed/31159750 http://dx.doi.org/10.1186/s12882-019-1342-x |
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