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Illumina error correction near highly repetitive DNA regions improves de novo genome assembly
BACKGROUND: Several standalone error correction tools have been proposed to correct sequencing errors in Illumina data in order to facilitate de novo genome assembly. However, in a recent survey, we showed that state-of-the-art assemblers often did not benefit from this pre-correction step. We found...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545690/ https://www.ncbi.nlm.nih.gov/pubmed/31159722 http://dx.doi.org/10.1186/s12859-019-2906-2 |