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Impaired Mitochondrial Fusion and Oxidative Phosphorylation Triggered by High Glucose Is Mediated by Tom22 in Endothelial Cells

Much evidence demonstrates that mitochondrial dysfunction plays a crucial role in the pathogenesis of vascular complications of diabetes. However, the signaling pathways through which hyperglycemia leads to mitochondrial dysfunction of endothelial cells are not fully understood. Here, we treated hum...

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Detalles Bibliográficos
Autores principales: Zeng, Yi, Pan, Qi, Wang, Xiaoxia, Li, Dongxiao, Lin, Yajun, Man, Fuli, Xiao, Fei, Guo, Lixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545771/
https://www.ncbi.nlm.nih.gov/pubmed/31236191
http://dx.doi.org/10.1155/2019/4508762