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In Silico Analysis of Coding/Noncoding SNPs of Human RETN Gene and Characterization of Their Impact on Resistin Stability and Structure

Resistin (RETN) is a gene coding for proinflammatory adipokine called resistin secreted by macrophages in humans. Single nucleotide polymorphisms (SNPs) in RETN are linked to obesity and insulin resistance in various populations. Using dbSNP, 78 nonsynonymous SNPs (nsSNPs) were retrieved and tested...

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Detalles Bibliográficos
Autores principales: Elkhattabi, Lamiae, Morjane, Imane, Charoute, Hicham, Amghar, Soumaya, Bouafi, Hind, Elkarhat, Zouhair, Saile, Rachid, Rouba, Hassan, Barakat, Abdelhamid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545779/
https://www.ncbi.nlm.nih.gov/pubmed/31236417
http://dx.doi.org/10.1155/2019/4951627