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Remodeling of Substance P Sensory Nerves and Transient Receptor Potential Melastatin 8 (TRPM8) Cold Receptors After Corneal Experimental Surgery

PURPOSE: To investigate changes in corneal nerves positive to substance P (SP) and transient receptor potential melastatin 8 (TRPM8) and gene expression in the trigeminal ganglia (TG) following corneal surgery to unveil peripheral nerve mechanism of induced dry eye-like pain (DELP). METHODS: Surgery...

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Detalles Bibliográficos
Autores principales: He, Jiucheng, Pham, Thang Luong, Kakazu, Azucena H., Bazan, Haydee E. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545819/
https://www.ncbi.nlm.nih.gov/pubmed/31157834
http://dx.doi.org/10.1167/iovs.18-26384