Unraveling the cellular origin and clinical prognostic markers of infant B-cell acute lymphoblastic leukemia using genome-wide analysis

B-cell acute lymphoblastic leukemia is the commonest childhood cancer. In infants, B-cell acute lymphoblastic leukemia remains fatal, especially in patients with t(4;11), present in ~80% of cases. The pathogenesis of t(4;11)/KMT2A-AFF1(+) (MLL-AF4(+)) infant B-cell acute lymphoblastic leukemia remai...

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Detalles Bibliográficos
Autores principales: Agraz-Doblas, Antonio, Bueno, Clara, Bashford-Rogers, Rachael, Roy, Anindita, Schneider, Pauline, Bardini, Michela, Ballerini, Paola, Cazzaniga, Gianni, Moreno, Thaidy, Revilla, Carlos, Gut, Marta, Valsecchi, Maria G., Roberts, Irene, Pieters, Rob, De Lorenzo, Paola, Varela, Ignacio, Menendez, Pablo, Stam, Ronald W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545849/
https://www.ncbi.nlm.nih.gov/pubmed/30679323
http://dx.doi.org/10.3324/haematol.2018.206375

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545849/
https://www.ncbi.nlm.nih.gov/pubmed/30679323
http://dx.doi.org/10.3324/haematol.2018.206375

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