Ccr4–Not maintains genomic integrity by controlling the ubiquitylation and degradation of arrested RNAPII

The Ccr4–Not complex regulates essentially every aspect of gene expression, from mRNA synthesis to protein destruction. The Not4 subunit of the complex contains an E3 RING domain and targets proteins for ubiquitin-dependent proteolysis. Ccr4–Not associates with elongating RNA polymerase II (RNAPII),...

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Detalles Bibliográficos
Autores principales: Jiang, Haoyang, Wolgast, Marley, Beebe, Laura M., Reese, Joseph C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546055/
https://www.ncbi.nlm.nih.gov/pubmed/30948432
http://dx.doi.org/10.1101/gad.322453.118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546055/
https://www.ncbi.nlm.nih.gov/pubmed/30948432
http://dx.doi.org/10.1101/gad.322453.118

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