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Resilience of BST-2/Tetherin structure to single amino acid substitutions

Human tetherin, also known as BST-2 or CD317, is a dimeric, extracellular membrane-bound protein that consists of N and C terminal membrane anchors connected by an extracellular domain. BST-2 is involved in binding enveloped viruses, such as HIV, and inhibiting viral release in addition to a role in...

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Detalles Bibliográficos
Autores principales: Roy, Ian R., Sutton, Camden K., Berndsen, Christopher E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546079/
https://www.ncbi.nlm.nih.gov/pubmed/31183261
http://dx.doi.org/10.7717/peerj.7043