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Long Term Exposure to Tenofovir Disoproxil Fumarate-Containing Antiretroviral Therapy Is Associated with Renal Impairment in an African Cohort of HIV-Infected Adults

OBJECTIVES AND METHOD: There are growing concerns of tenofovir disoproxil fumarate (TDF)–associated renal toxicity. We evaluated the effect of long-term TDF exposure on renal function in a cohort of HIV-1-infected Nigerians between 2006 and 2015. Multivariate logistic regression was used to identify...

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Detalles Bibliográficos
Autores principales: Agbaji, Oche O., Abah, Isaac O., Ebonyi, Augustine O., Gimba, Zumnan M., Abene, Esla E., Gomerep, Simji S., Falang, Kakjing D., Anejo-Okopi, Joseph, Agaba, Patricia A., Ugoagwu, Placid O., Agaba, Emmanuel I., Imade, Godwin E., Sagay, Atiene S., Okonkwo, Prosper, Idoko, John A., Kanki, Phyllis J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546287/
https://www.ncbi.nlm.nih.gov/pubmed/30672363
http://dx.doi.org/10.1177/2325958218821963