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Perturbation of mRNP biogenesis reveals a dynamic landscape of the Rrp6-dependent surveillance machinery trafficking along the yeast genome

Eukaryotic cells have evolved a nuclear quality control (QC) system to monitor the co-transcriptional mRNA processing and packaging reactions that lead to the formation of export-competent ribonucleoprotein particles (mRNPs). Aberrant mRNPs that fail to pass the QC steps are retained in the nucleus...

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Detalles Bibliográficos
Autores principales: Moreau, Kévin, Le Dantec, Aurélia, Mosrin-Huaman, Christine, Bigot, Yves, Piégu, Benoit, Rahmouni, A. Rachid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546349/
https://www.ncbi.nlm.nih.gov/pubmed/31007122
http://dx.doi.org/10.1080/15476286.2019.1593745