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CRISPR-Cas in Streptococcus pyogenes

The discovery and characterization of the prokaryotic CRISPR-Cas immune system has led to a revolution in genome editing and engineering technologies. Despite the fact that most applications emerged after the discovery of the type II-A CRISPR-Cas9 system of Streptococcus pyogenes, its biological imp...

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Detalles Bibliográficos
Autores principales: Le Rhun, Anaïs, Escalera-Maurer, Andrés, Bratovič, Majda, Charpentier, Emmanuelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546361/
https://www.ncbi.nlm.nih.gov/pubmed/30856357
http://dx.doi.org/10.1080/15476286.2019.1582974