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Asymmetry between the two acidic patches dictates the direction of nucleosome sliding by the ISWI chromatin remodeler
The acidic patch is a functionally important epitope on each face of the nucleosome that affects chromatin remodeling. Although related by 2-fold symmetry of the nucleosome, each acidic patch is uniquely positioned relative to a bound remodeler. An open question is whether remodelers are distinctly...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546392/ https://www.ncbi.nlm.nih.gov/pubmed/31094676 http://dx.doi.org/10.7554/eLife.45472 |