Knockdown of TRIM65 inhibits autophagy and cisplatin resistance in A549/DDP cells by regulating miR-138-5p/ATG7

Cisplatin resistance is the main cause of treatment failure in patients with non-small-cell lung cancer (NSCLC). Autophagy is a key mechanism of resistance to chemotherapy. Given that tripartite motif (TRIM)-containing proteins are involved in the regulation of autophagy and chemoresistance, we aime...

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Detalles Bibliográficos
Autores principales: Pan, Xufeng, Chen, Yong, Shen, Yuzhou, Tantai, Jicheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546683/
https://www.ncbi.nlm.nih.gov/pubmed/31160576
http://dx.doi.org/10.1038/s41419-019-1660-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546683/
https://www.ncbi.nlm.nih.gov/pubmed/31160576
http://dx.doi.org/10.1038/s41419-019-1660-8

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