Wwp2 maintains cartilage homeostasis through regulation of Adamts5

The WW domain-containing protein 2 (Wwp2) gene, the host gene of miR-140, codes for the Wwp2 protein, which is an HECT-type E3 ubiquitin ligases abundantly expressed in articular cartilage. However, its function remains unclear. Here, we show that mice lacking Wwp2 and mice in which the Wwp2 E3 enzy...

Descripción completa

Detalles Bibliográficos
Autores principales: Mokuda, Sho, Nakamichi, Ryo, Matsuzaki, Tokio, Ito, Yoshiaki, Sato, Tempei, Miyata, Kohei, Inui, Masafumi, Olmer, Merissa, Sugiyama, Eiji, Lotz, Martin, Asahara, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546747/
https://www.ncbi.nlm.nih.gov/pubmed/31160553
http://dx.doi.org/10.1038/s41467-019-10177-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546747/
https://www.ncbi.nlm.nih.gov/pubmed/31160553
http://dx.doi.org/10.1038/s41467-019-10177-1

Ejemplares similares