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Reduction in H3K4me patterns due to aberrant expression of methyltransferases and demethylases in renal cell carcinoma: prognostic and therapeutic implications

Renal cell carcinoma (RCC) is the leading cause among cancer-related deaths due to urological cancers, which results in response to combination of genetic and epigenetic factors. Histone methylations have been implicated in renal tumorigenesis but their clinical significance and underlying pathology...

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Detalles Bibliográficos
Autores principales: Kumar, Aman, Kumari, Niti, Sharma, Ujjawal, Ram, Sant, Singh, Shrawan Kumar, Kakkar, Nandita, Kaushal, Karanvir, Prasad, Rajendra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546756/
https://www.ncbi.nlm.nih.gov/pubmed/31160694
http://dx.doi.org/10.1038/s41598-019-44733-y