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Elimination of tumor hypoxia by eribulin demonstrated by (18)F-FMISO hypoxia imaging in human tumor xenograft models
BACKGROUND: Eribulin, an inhibitor of microtubule dynamics, shows antitumor potency against a variety of solid cancers through its antivascular activity and remodeling of tumor vasculature. (18)F-Fluoromisonidazole ((18)F-FMISO) is the most widely used PET probe for imaging tumor hypoxia. In this st...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546772/ https://www.ncbi.nlm.nih.gov/pubmed/31161539 http://dx.doi.org/10.1186/s13550-019-0521-x |