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Hes1 expression in mature neurons in the adult mouse brain is required for normal behaviors

Hes1 regulates the maintenance and proliferation of neural stem/progenitor cells as an essential effector of the Notch signaling pathway. Although Notch signaling is also involved in the functions of mature neurons in learning and memory and in the risk factors for mental disorders such as schizophr...

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Detalles Bibliográficos
Autores principales: Matsuzaki, Tadanobu, Yoshihara, Toru, Ohtsuka, Toshiyuki, Kageyama, Ryoichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546782/
https://www.ncbi.nlm.nih.gov/pubmed/31160641
http://dx.doi.org/10.1038/s41598-019-44698-y