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Hes1 expression in mature neurons in the adult mouse brain is required for normal behaviors
Hes1 regulates the maintenance and proliferation of neural stem/progenitor cells as an essential effector of the Notch signaling pathway. Although Notch signaling is also involved in the functions of mature neurons in learning and memory and in the risk factors for mental disorders such as schizophr...
Autores principales: | Matsuzaki, Tadanobu, Yoshihara, Toru, Ohtsuka, Toshiyuki, Kageyama, Ryoichiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546782/ https://www.ncbi.nlm.nih.gov/pubmed/31160641 http://dx.doi.org/10.1038/s41598-019-44698-y |
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