Human evolved regulatory elements modulate genes involved in cortical expansion and neurodevelopmental disease susceptibility

Modern genetic studies indicate that human brain evolution is driven primarily by changes in gene regulation, which requires understanding the biological function of largely non-coding gene regulatory elements, many of which act in tissue specific manner. We leverage chromatin interaction profiles i...

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Detalles Bibliográficos
Autores principales: Won, Hyejung, Huang, Jerry, Opland, Carli K., Hartl, Chris L., Geschwind, Daniel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546784/
https://www.ncbi.nlm.nih.gov/pubmed/31160561
http://dx.doi.org/10.1038/s41467-019-10248-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546784/
https://www.ncbi.nlm.nih.gov/pubmed/31160561
http://dx.doi.org/10.1038/s41467-019-10248-3

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