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Human evolved regulatory elements modulate genes involved in cortical expansion and neurodevelopmental disease susceptibility
Modern genetic studies indicate that human brain evolution is driven primarily by changes in gene regulation, which requires understanding the biological function of largely non-coding gene regulatory elements, many of which act in tissue specific manner. We leverage chromatin interaction profiles i...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546784/ https://www.ncbi.nlm.nih.gov/pubmed/31160561 http://dx.doi.org/10.1038/s41467-019-10248-3 |