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Fbxo41 Promotes Disassembly of Neuronal Primary Cilia

Neuronal primary cilia are signaling organelles with crucial roles in brain development and disease. Cilia structure is decisive for their signaling capacities but the mechanisms regulating it are poorly understood. We identify Fbxo41 as a novel Skp1/Cullin1/F-box (SCF) E3-ligase complex subunit tha...

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Detalles Bibliográficos
Autores principales: King, Cillian R., A. A. Quadros, Ana R., Chazeau, Anaël, Saarloos, Ingrid, van der Graaf, Anne Jolien, Verhage, Matthijs, Toonen, Ruud F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546786/
https://www.ncbi.nlm.nih.gov/pubmed/31160656
http://dx.doi.org/10.1038/s41598-019-44589-2