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Growth Inhibitory Effects of Dipotassium Glycyrrhizinate in Glioblastoma Cell Lines by Targeting MicroRNAs Through the NF-κB Signaling Pathway

It has been shown that nuclear factor kappa-B (NF-κB) is constitutively activated in glioblastoma (GBM), suggesting that the pathway could be a therapeutic target. Glycyrrhetic acid (GA), a compound isolated from licorice (Glycyrrhiza glabra), has been shown to decrease cell viability and increases...

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Detalles Bibliográficos
Autores principales: Bonafé, Gabriel Alves, dos Santos, Jéssica Silva, Ziegler, Jussara Vaz, Umezawa, Kazuo, Ribeiro, Marcelo Lima, Rocha, Thalita, Ortega, Manoela Marques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546822/
https://www.ncbi.nlm.nih.gov/pubmed/31191251
http://dx.doi.org/10.3389/fncel.2019.00216