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Methylome Dynamics of Bovine Gametes and in vivo Early Embryos

DNA methylation undergoes drastic fluctuation during early mammalian embryogenesis. The dynamics of global DNA methylation in bovine embryos, however, have mostly been studied by immunostaining. We adopted the whole genome bisulfite sequencing (WGBS) method to characterize stage-specific genome-wide...

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Detalles Bibliográficos
Autores principales: Duan, Jingyue Ellie, Jiang, Zongliang Carl, Alqahtani, Fahad, Mandoiu, Ion, Dong, Hong, Zheng, Xinbao, Marjani, Sadie L., Chen, Jingbo, Tian, Xiuchun Cindy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546829/
https://www.ncbi.nlm.nih.gov/pubmed/31191619
http://dx.doi.org/10.3389/fgene.2019.00512