Sublethal whole-body irradiation causes progressive premature frailty in mice

There is an unmet need to develop and validate therapies that can treat or at least prevent premature therapy-induced frailty, multi-morbidity and mortality in long-term tumour survivors. In an approach to develop a first mouse model for therapy-induced long-term frailty, we irradiated male C57Bl/6...

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Detalles Bibliográficos
Autores principales: Fielder, Edward, Weigand, Melanie, Agneessens, Julien, Griffin, Brigid, Parker, Craig, Miwa, Satomi, von Zglinicki, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ireland 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546927/
https://www.ncbi.nlm.nih.gov/pubmed/30954485
http://dx.doi.org/10.1016/j.mad.2019.03.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546927/
https://www.ncbi.nlm.nih.gov/pubmed/30954485
http://dx.doi.org/10.1016/j.mad.2019.03.006

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