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Sublethal whole-body irradiation causes progressive premature frailty in mice
There is an unmet need to develop and validate therapies that can treat or at least prevent premature therapy-induced frailty, multi-morbidity and mortality in long-term tumour survivors. In an approach to develop a first mouse model for therapy-induced long-term frailty, we irradiated male C57Bl/6...
Autores principales: | Fielder, Edward, Weigand, Melanie, Agneessens, Julien, Griffin, Brigid, Parker, Craig, Miwa, Satomi, von Zglinicki, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science Ireland
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546927/ https://www.ncbi.nlm.nih.gov/pubmed/30954485 http://dx.doi.org/10.1016/j.mad.2019.03.006 |
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