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Syndromic surveillance of potentially epidemic infectious diseases: Detection of a measles epidemic in two health centers in Gabon, Central Africa

Measles is a respiratory disease caused by the measles virus (MV) belonging to the Paramyxovirus family and the Morbillivirus genus. Due to a failure in maintaining immunization coverage in some countries, measles is a re-emerging disease in the human population, especially in Africa. The aim of thi...

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Autores principales: Sir-Ondo-Enguier, Pater Noster, Ngoungou, Edgard Brice, Nghomo, Yves-Noel, Boundenga, Larson, Moupiga-Ndong, Priscille, IBINGA, Euloge, Deparis, Xavier, Lékana-Douki, Jean-Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547028/
https://www.ncbi.nlm.nih.gov/pubmed/31205640
http://dx.doi.org/10.4081/idr.2019.7701
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author Sir-Ondo-Enguier, Pater Noster
Ngoungou, Edgard Brice
Nghomo, Yves-Noel
Boundenga, Larson
Moupiga-Ndong, Priscille
IBINGA, Euloge
Deparis, Xavier
Lékana-Douki, Jean-Bernard
author_facet Sir-Ondo-Enguier, Pater Noster
Ngoungou, Edgard Brice
Nghomo, Yves-Noel
Boundenga, Larson
Moupiga-Ndong, Priscille
IBINGA, Euloge
Deparis, Xavier
Lékana-Douki, Jean-Bernard
author_sort Sir-Ondo-Enguier, Pater Noster
collection PubMed
description Measles is a respiratory disease caused by the measles virus (MV) belonging to the Paramyxovirus family and the Morbillivirus genus. Due to a failure in maintaining immunization coverage in some countries, measles is a re-emerging disease in the human population, especially in Africa. The aim of this study was to describe a measles epidemic in Gabon. At first, a syndromic surveillance was set up. Blood samples from febrile patients with maculopapular rash were taken and sent to the measles reference center in Cameroon for laboratory confirmation. Between March and May 2016, 79 clinically suspected cases were reported including 82.3% (n=65) and 17.7% (n=14) in Oyem and Libreville, respectively. In total, 39.2% (n=31) of children were 11 months-old, 34.2% (n=27) were children aged 1 to 4 years, 11.4% (n=9) were older children from 5 to 9 years, 6.3% (n=5) of children were aged 10 to 15 years and 8.9% (n=7) were 15 years and older. 53.3% (16/30) were laboratory confirmed. This measles outbreak reiterates the importance of maintaining a high level of vaccine coverage in Gabon for vaccine-preventable diseases, as well as the usefulness of a near-real-time surveillance system for the detection of infectious diseases.
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spelling pubmed-65470282019-06-14 Syndromic surveillance of potentially epidemic infectious diseases: Detection of a measles epidemic in two health centers in Gabon, Central Africa Sir-Ondo-Enguier, Pater Noster Ngoungou, Edgard Brice Nghomo, Yves-Noel Boundenga, Larson Moupiga-Ndong, Priscille IBINGA, Euloge Deparis, Xavier Lékana-Douki, Jean-Bernard Infect Dis Rep Article Measles is a respiratory disease caused by the measles virus (MV) belonging to the Paramyxovirus family and the Morbillivirus genus. Due to a failure in maintaining immunization coverage in some countries, measles is a re-emerging disease in the human population, especially in Africa. The aim of this study was to describe a measles epidemic in Gabon. At first, a syndromic surveillance was set up. Blood samples from febrile patients with maculopapular rash were taken and sent to the measles reference center in Cameroon for laboratory confirmation. Between March and May 2016, 79 clinically suspected cases were reported including 82.3% (n=65) and 17.7% (n=14) in Oyem and Libreville, respectively. In total, 39.2% (n=31) of children were 11 months-old, 34.2% (n=27) were children aged 1 to 4 years, 11.4% (n=9) were older children from 5 to 9 years, 6.3% (n=5) of children were aged 10 to 15 years and 8.9% (n=7) were 15 years and older. 53.3% (16/30) were laboratory confirmed. This measles outbreak reiterates the importance of maintaining a high level of vaccine coverage in Gabon for vaccine-preventable diseases, as well as the usefulness of a near-real-time surveillance system for the detection of infectious diseases. PAGEPress Publications, Pavia, Italy 2019-05-23 /pmc/articles/PMC6547028/ /pubmed/31205640 http://dx.doi.org/10.4081/idr.2019.7701 Text en ©Copyright P.N. Sir-Ondo-Enguieret al., 2019 http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Article
Sir-Ondo-Enguier, Pater Noster
Ngoungou, Edgard Brice
Nghomo, Yves-Noel
Boundenga, Larson
Moupiga-Ndong, Priscille
IBINGA, Euloge
Deparis, Xavier
Lékana-Douki, Jean-Bernard
Syndromic surveillance of potentially epidemic infectious diseases: Detection of a measles epidemic in two health centers in Gabon, Central Africa
title Syndromic surveillance of potentially epidemic infectious diseases: Detection of a measles epidemic in two health centers in Gabon, Central Africa
title_full Syndromic surveillance of potentially epidemic infectious diseases: Detection of a measles epidemic in two health centers in Gabon, Central Africa
title_fullStr Syndromic surveillance of potentially epidemic infectious diseases: Detection of a measles epidemic in two health centers in Gabon, Central Africa
title_full_unstemmed Syndromic surveillance of potentially epidemic infectious diseases: Detection of a measles epidemic in two health centers in Gabon, Central Africa
title_short Syndromic surveillance of potentially epidemic infectious diseases: Detection of a measles epidemic in two health centers in Gabon, Central Africa
title_sort syndromic surveillance of potentially epidemic infectious diseases: detection of a measles epidemic in two health centers in gabon, central africa
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547028/
https://www.ncbi.nlm.nih.gov/pubmed/31205640
http://dx.doi.org/10.4081/idr.2019.7701
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