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Expression and purification optimization of an N-terminal Pfs230 transmission-blocking vaccine candidate

In an effort to control and eventually eliminate malaria, the development of transmission-blocking vaccines has long been sought. However, few antigens have been evaluated in clinical trials, often due to limitations in the expression and purification of the antigen in sufficient yield and quality....

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Detalles Bibliográficos
Autores principales: Lee, Shwu-Maan, Plieskatt, Jordan, Krishnan, Seetha, Raina, Monika, Harishchandra, Rakeshkumar, King, C. Richter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547048/
https://www.ncbi.nlm.nih.gov/pubmed/30978392
http://dx.doi.org/10.1016/j.pep.2019.04.001