Engineering repressors with coevolutionary cues facilitates toggle switches with a master reset

Engineering allosteric transcriptional repressors containing an environmental sensing module (ESM) and a DNA recognition module (DRM) has the potential to unlock a combinatorial set of rationally designed biological responses. We demonstrated that constructing hybrid repressors by fusing distinct ES...

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Detalles Bibliográficos
Autores principales: Dimas, Rey P, Jiang, Xian-Li, Alberto de la Paz, Jose, Morcos, Faruck, Chan, Clement T Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Synthetic Biology and Bioengineering
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547410/
https://www.ncbi.nlm.nih.gov/pubmed/31162606
http://dx.doi.org/10.1093/nar/gkz280

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547410/
https://www.ncbi.nlm.nih.gov/pubmed/31162606
http://dx.doi.org/10.1093/nar/gkz280

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