Bacterial Ligase D preternary-precatalytic complex performs efficient abasic sites processing at double strand breaks during nonhomologous end joining

Abasic (AP) sites, the most common DNA lesions are frequently associated with double strand breaks (DSBs) and can pose a block to the final ligation. In many prokaryotes, nonhomologous end joining (NHEJ) repair of DSBs relies on a two-component machinery constituted by the ring-shaped DNA-binding Ku...

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Detalles Bibliográficos
Autores principales: de Ory, Ana, Carabaña, Claudia, de Vega, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547435/
https://www.ncbi.nlm.nih.gov/pubmed/30976810
http://dx.doi.org/10.1093/nar/gkz265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547435/
https://www.ncbi.nlm.nih.gov/pubmed/30976810
http://dx.doi.org/10.1093/nar/gkz265

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