N-terminal residues of human dyskerin are required for interactions with telomerase RNA that prevent RNA degradation

The telomerase holoenzyme responsible for maintaining telomeres in vertebrates requires many components in vivo, including dyskerin. Dyskerin binds and regulates the accumulation of the human telomerase RNA, hTR, as well as other non-coding RNAs that share the conserved H/ACA box motif. The precise...

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Detalles Bibliográficos
Autores principales: MacNeil, Deanna E, Lambert-Lanteigne, Patrick, Autexier, Chantal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547437/
https://www.ncbi.nlm.nih.gov/pubmed/30931479
http://dx.doi.org/10.1093/nar/gkz233

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547437/
https://www.ncbi.nlm.nih.gov/pubmed/30931479
http://dx.doi.org/10.1093/nar/gkz233

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