The HRP3 PWWP domain recognizes the minor groove of double-stranded DNA and recruits HRP3 to chromatin

HDGF-related protein 3 (HRP3, also known as HDGFL3) belongs to the family of HDGF-related proteins (HRPs) and plays an essential role in hepatocellular carcinoma pathogenesis. All HRPs have a PWWP domain at the N-terminus that binds both histone and DNA substrates. Despite previous advances in PWWP...

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Detalles Bibliográficos
Autores principales: Tian, Wei, Yan, Peiqiang, Xu, Ning, Chakravorty, Arghya, Liefke, Robert, Xi, Qiaoran, Wang, Zhanxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547440/
https://www.ncbi.nlm.nih.gov/pubmed/31162607
http://dx.doi.org/10.1093/nar/gkz294

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547440/
https://www.ncbi.nlm.nih.gov/pubmed/31162607
http://dx.doi.org/10.1093/nar/gkz294

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