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Predictive models of eukaryotic transcriptional regulation reveals changes in transcription factor roles and promoter usage between metabolic conditions

Transcription factors (TF) are central to transcriptional regulation, but they are often studied in relative isolation and without close control of the metabolic state of the cell. Here, we describe genome-wide binding (by ChIP-exo) of 15 yeast TFs in four chemostat conditions that cover a range of...

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Detalles Bibliográficos
Autores principales: Holland, Petter, Bergenholm, David, Börlin, Christoph S, Liu, Guodong, Nielsen, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547448/
https://www.ncbi.nlm.nih.gov/pubmed/30976803
http://dx.doi.org/10.1093/nar/gkz253